Had time to think on it now.
The bad - as pointed out, the "de-aging" effects were distracting and they couldn't mask the fact that De Niro is an old man. Watching him try to beat up the shopkeeper in the street was cringe-worthy as you could see he had difficulty moving. There was none of the caged violent energy shown when he was a younger actor. The scene where he gingerly steps over rocks to throw a gun in the river was like watching your grandad - I was scared he was going to fall and hurt himself. Pacino didn't have the physical limitations of De Niro, but he wasn't asked to do anything strenuous. At times with the ensemble cast, it was like going to watch the Rolling Stones. Standard humdrum fare lit up now and again with a recognisable guitar riff - De Niro's self deprecating smile or Pacino's wide-eyed astonishment, mannerisms that we know from a dozen classic films.
Whilst the women in the film were very much peripheral characters, I thought Frank's daughter was used to remind the viewer - and Frank - where normal human behaviour starts and stops. Throughout the film Frank constantly seeks her approval and it's his daughter who shames him into calling Hoffa's widow - a fantastic scene in itself.
The last half hour was, for me, superb. In fact the last hour and a half when Pacino, Pesci and De Niro started playing their actual ages was great. No need to pretend these were violent men to be scared of, but we came to see that as death approaches we all take stock of our lives and find what was really important. Frank's slide into enfeeblement is done well by De Niro.